Jobid=626503846206637948 (0.0985)
Are you passionate about combining microfluidic technology, material science, device engineering, and cell therapeutic strategies towards real-world applications ? We offer an impactful postdoc position in the Leijten Laboratory within the Department of BioEngineering Technologies as part of a recently funded National consortium (NWO-Perspectief: RecovAir). In this consortium, we develop novel delivery methods for lung therapeutics by microfluidic devices, nanomaterials, pharmacological compounds, advanced in vitro models, and therapeutic cells. This approach represents a beyond-state-of-the-art solution to treat COPD.
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You will use a highly advanced microfluidic devices that was recently invented in our department (patent pending) to next-generation micromaterials that will be used by the consortium parters for COPD therapy. You will explore the development and fabrication of the microfluidic device strategies to improve its functional performances and investigate the function of the produced (living) microgels. Moreover, you will investigate this novel microfluidic platform’s capacity for full aqueous (ATPS) production at MHz speeds, which will improve current production rates by multiple orders of magnitude. This will be achieved by exploring a physics principle that was previously not used in microfluidic devices. Not only does this provide an exciting and unique fundamental academic challenges that pushes the limits of our knowledge, but it also offers immediate entrepreneurial/commercial applications that can be explored via valorisation of the patent. Furthermore, you will interface with a variety of clinicians, cell biologists and pharmacologists to explore a novel method for regenerating lung tissue. You will therefore work on the multidisciplinary interface of microtechnology, materials science, physics, engineering, and (stem)cell biology. You will thereby be trained to develop a wide skill set, which will include microdevice fabrication, micromaterial production, cell encapsulation, advanced (photo)polymerization, materials characterization, state of the art cell culture, and writing high impact scientific publications. Moreover, it possible for the postdoc to explore the possibility to found a spin-off company to valorise the patent and associate technology, for which UT can provide further skill training and support.
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